Hotel Del Luna tells the story of Jang Man Wol (IU), the hotel owner who made a big mistake in the past. Unlike her elegant, critical, fussy, skeptical, greedy, and extravagant appearance, Jang Man Wol lives in her own hotel called Hotel Del Luna in a very boring way, as if time has stopped.
Meanwhile, Goo Chan Sung (Yeo Jin Goo) is a manager at an elite hotel. Goo Chan Sung is very perfectionist and has ailments such as obsessive-compulsive disorder, obsession with hygiene, to paranoid. Goo Chan Sung looks calm and rational but in reality, he is a timid man.
Thanks to his perfectionist nature, Goo Chan Sung’s career has skyrocketed and became the youngest deputy manager in a multinational hotel group. Everything went smoothly, until finally through an unexpected event, Goo Chan Sung was forced to become a manager at the Del Luna hotel and was tasked with welcoming customers who were ghosts. Hotel Del Luna itself is a hotel that has long stood with an old-fashioned appearance and is located in downtown Seoul. The hotel is said to be a residence of the ghosts.